Xenbase Image ID: 152432

Fig. 2. Comparison of the exon-centric and junction-centric approaches to identify differential splicing patterns in Xenopus laevis. A, RNAseq was carried out from 3 independent pools of stage 28 embryos injected with the morpholino against ptbp1 mRNA (ptbp1 MO), or left uninjected. B, Table summarizing RNAseq data. “% mapped” is to the percentage of read pairs uniquely mapped to the Xenopus genome (v9.1). C, Venn diagram showing the overlap of the genes with at least one differential exon, the genes with at least one annotation-supported differential junction, and the genes with at least one differential junction. D, For the 304 (284+20) genes with at least one differential exon and one differential junction, we indicate the numbers of differential exons and junctions. The pie charts show the percentage of differential exons associated with one differential junction (left), and the percentage of differential junctions associated with one differential exon (right). E, Comparison of enriched GO terms in differentially spliced genes identified by the junction-centric and the exon-centric approaches. The dotted red line indicates p=0.05. The GO terms are on the left, and we clustered the enriched GO terms in 4 main classes (right). Image published in: Noiret M et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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