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Figure 5. Heterotaxia Following Misexpression of H+/K+-ATPase α and β Subunits and the Kir4.1 Potassium Channel Xenopus embryos were injected at the 1-cell stage with mRNAs encoding H+/K+-ATPase α and β subunits and Kir4.1. The incidence of heterotaxia (percentage of heterotaxic embryos) was scored as in Figure 1. α and β subunits expressed together, but not alone, induced statistically significant (*, p < 0.001) incidence of heterotaxia. Kir4.1 further increased the incidence of heterotaxic embryos when coexpressed with both H+/K+-ATPase subunits.

Image published in: Levin M et al. (2002)

Copyright © 2002. Image reproduced with permission of the Publisher, Elsevier B. V.

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