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Figure S5. Pro-survival Mcl1 is expressed in the axonal compartment. (A) Complements Fig. 8A: Optic nerve head (ONH) region of a stage 43 wild-type retina (coronal section) probed for Mcl1 and counterstained with DAPI. Mcl1 was detected in the optic fiber layer and the optic nerve head, indicating that, like Tctp, this protein localizes to retinal ganglion cell axons in vivo. (B) Complements Fig. 8A: Outer nuclear layer of a stage 43 wild-type retina (coronal section) probed for Mcl1 and Rhodopsin, and counterstained with DAPI. Similar to Tctp, Mcl1 was detected in the inner segment of photoreceptors. (C and D) Cultured rat cortical neurons (E18.5 + 3DIV) stained for Mcl1 or Tctp, and counterstained with Phalloidin. Scale bars: 25 μm in (A), (C) and (D), 10 μm in (B). Image published in: Roque CG et al. (2016) © 2016. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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