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Figure 5. Altered chamber morphology in muz heartsCoronal plastic sections of stage 40 wild type and muz hearts (top rows) numbered from ventral side of cardiac cavity, and indicated by white lines in 3D models (bottom rows). m= myocardium, e= inner endocardial tube, v= ventricle, ot= outflow tract , a= atrium. No blood cells are seen in the muz sections due to lack of circulation, and myocardial layer appears thinner throughout the muz heart compared to wild type. The muz ventricle is wider than in wild type (sections 7 and 11), while outflow tract and atrium are dilated (sections 14, 23 and 41). Abnormal muz chamber morphology is highlighted in 3D projections of outlines of myocardium (A, C, E, G, red=ventricle, blue=outflow tract, green=atrium) and endocardium (B, D, F, H, orange), including elongated ventricle, dilated outflow tract (black arrowhead in E) and narrow cardiac tube at AVC level (black arrow in G). muz endocardium is very compressed with drastically reduced lumen (white arrows in 23, F and H)

Image published in: Abu-Daya A et al. (2009)

Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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