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Fig. 3. An unrooted phylogenetic tree of Igs in vertebrates. The tree was constructed by using protein sequences of the first and last CH domains (fish δCH6 and Xenopus δCH7 were used as the last domain) of all heavy-chain classes. Except for the Ig sequences obtained in this study, all other sequences were taken from the GenBank database, with the following accession numbers: Cδ gene: catfish (AF363450), fugu (AB159481), human (BC021276), mouse (J00449), and zebrafish (BX510335); Cμ gene: catfish (M27230), chicken (X01613), duck (AJ314750), human (X14940), mouse (V00818), nurse shark (M92851), little skate (M29679), X. laevis (BC084123), and zebrafish (AY643751); Cα gene: chicken (S40610), cow (AF109617), duck (U27222), human (P01877), and mouse (BC010324); Cε gene: cow (BTU63640), human (AK130825), and mouse (X01857); Cγ gene: cow (S82407), human (BX640623), llama (AF305955), and mouse (AY498569); Cυ gene: chicken (X07174), duck (AJ314754), and X. laevis (X15114); and Cχ gene: X. laevis (BC072981), nurse shark NAR (U18701), sandbar shark IgW (U40560), and lungfish IgW (AF437727).

Image published in: Zhao Y et al. (2006)

Copyright © 2006. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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