XB-IMG-153203
Xenbase Image ID: 153203
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Figure 1.
frzb-1 mRNA Expression in Xenopus, Mouse, and Human
(A–D) Double-labeled in situ hybridization of Xenopus embryos showing frzb-1 (blue) and chordin expression (brown). (A) shows the vegetal view at stage 11; (B), lateral view of stage 13 embryo; (C), dorsal view of the same embryo; and (D), tailbud stage embryo.
(E–J) Expression of frzb-1 in manipulated embryos. (E) shows the vegetal view of a Xenopus gastrula dorsalized by LiCl treatment; (F), Xenopus gastrula ventralized by UV irradiation; (G), vegetal view of an untreated embryo (stage 10 1/2); (H), Vegetal view of an embryo (stage 10 1/2) radially injected with siamois RNA; (I), frzb-1 expression in a stage 10 1/2 embryo radially injected with activated Xlim1 RNA; and (J), frzb-1 expression in a stage 10 1/2 embryo radially injected with goosecoid RNA.
(K) Mouse gastrula (midstreak stage) showing frzb-1 expression in the primitive streak.
(L) Mouse embryo (8.5 day) frzb-1 expression in the foregut diverticulum (arrowhead), nervous system, and posterior mesoderm.
(M–N) Northern blot of adult mouse tissue (M) and human tissue (N) showing frzb-1 expression in heart (H), brain (B), spleen (S), skeletal muscle (M), kidney (K), testis (T), placenta (Pl), and pancreas (Pa). frzb-1 is detected at very low levels in lung (Lu) and liver (Li). Image published in: Leyns L et al. (1997) Copyright © 1997. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |