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XB-IMG-153608

Xenbase Image ID: 153608


Fig. 4. Dependence of localization patterns on actin and tubulin organization. Microtubules were targeted by nocodazole from fertilization, as described in the Experimental Procedures section. Actin filaments were targeted by latrunculin from fertilization, as described in the Experimental Procedures section. KIF3B: sections taken perpendicular to the AV axis at the 2-cell stage in control embryos (A), and those in which microtubules (B) or actin filaments (C) were targeted. Polycystin-2: sections taken perpendicular to the AV axis at the 2-cell stage in control embryos (D), and those in which microtubules (E) or actin filaments (F) were targeted. Acetylated -tubulin: sections taken perpendicular to the AV axis at the 4-cell stage in control embryos (G), and those in which microtubules (H) or actin filaments (I) were targeted. LRD: sections taken parallel to the AV axis at the 2-cell stage in control embryos (J), and those in which microtubules (K) or actin filaments (L) were targeted. Polaris: sections taken perpendicular to the AV axis at the 4-cell stage in control embryos (M), and those in which microtubules (N) or actin filaments (O1–O4) were targeted. Inversin: sections taken parallel to the AV axis at the 8-cell stage in control embryos (P) or embryos in which microtubules (Q) or actin filaments (R) were targeted; sections taken perpendicular to the AV axis at the 4-cell stage in control embryos (S) and those in which microtubules (T) were targeted. U: In each panel, yellow ovals with their long axis oriented left to right indicate that the section was taken across the AV axis; yellow ovals with their long axes oriented vertically indicate that the section was taken along the AV axis, with the animal pole being upward. Red arrows, signal; white arrows, lack of signal; green arrows, additional signal.

Image published in: Qiu D et al. (2005)

Copyright © 2005. Image reproduced with permission of the Publisher, John Wiley & Sons.

GeneSynonymsSpeciesStage(s)Tissue
kif3b.Lkinesin-II, klp3, klp3b, LOC108702080, xklp3, xklp3bX. laevisThroughout NF stage 2 (2-cell) 
pkd2.LPC2, polycystin 2, polycystin-2, trpp2X. laevisThroughout NF stage 2 (2-cell) 
tuba4b.Lalpha tubulin, alpha-tubulin, tuba4, tuba4aX. laevisThroughout NF stage 2 (2-cell) 
dnah9.Ldnah9-A, L-R Dynein, Left-Right Dynein, LRDX. laevisThroughout NF stage 2 (2-cell) 
ift88.Lpolaris, tg737X. laevisThroughout NF stage 2 (2-cell) 
invs.Linversin, invs-a, invs-b, nephrocystin-2, NPH2, NPHP2X. laevisThroughout NF stage 2 (2-cell) 

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