XB-IMG-153608
Xenbase Image ID: 153608
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Fig. 4. Dependence of localization patterns on actin and
tubulin organization. Microtubules were targeted by nocodazole
from fertilization, as described in the Experimental Procedures
section. Actin filaments were targeted by latrunculin
from fertilization, as described in the Experimental Procedures
section. KIF3B: sections taken perpendicular to the
AV axis at the 2-cell stage in control embryos (A), and those
in which microtubules (B) or actin filaments (C) were targeted.
Polycystin-2: sections taken perpendicular to the AV
axis at the 2-cell stage in control embryos (D), and those in
which microtubules (E) or actin filaments (F) were targeted.
Acetylated -tubulin: sections taken perpendicular to the AV
axis at the 4-cell stage in control embryos (G), and those in
which microtubules (H) or actin filaments (I) were targeted.
LRD: sections taken parallel to the AV axis at the 2-cell stage
in control embryos (J), and those in which microtubules (K)
or actin filaments (L) were targeted. Polaris: sections taken
perpendicular to the AV axis at the 4-cell stage in control
embryos (M), and those in which microtubules (N) or actin
filaments (O1–O4) were targeted. Inversin: sections taken
parallel to the AV axis at the 8-cell stage in control embryos
(P) or embryos in which microtubules (Q) or actin filaments
(R) were targeted; sections taken perpendicular to the AV
axis at the 4-cell stage in control embryos (S) and those in
which microtubules (T) were targeted. U: In each panel,
yellow ovals with their long axis oriented left to right indicate
that the section was taken across the AV axis; yellow ovals
with their long axes oriented vertically indicate that the section
was taken along the AV axis, with the animal pole being
upward. Red arrows, signal; white arrows, lack of signal;
green arrows, additional signal. Image published in: Qiu D et al. (2005) Copyright © 2005. Image reproduced with permission of the Publisher, John Wiley & Sons.
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