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Fig. 3. Identification and syntenic analysis of clock genes. Phylogenetic analysis of Per (A), Cry (B), Clock (C), and Bmal (D). In circadian rhythms, there are two clock, two bmal, two cry, and three per genes in X. tropicalis, as in mammals. Using clock genes of X. tropicalis, we identified 15 homeolog candidates of X. laevis. Phylogenetic analysis indicated six homeolog pairs (clock.L/clock.S, bma1.L/bmal1.S, bmal2.L/bmal2.S, per3.L/per3.S, cry1.L/cry1.S, and cry2.L/cry2.S) and three singletons (per1.L, per2.L, and npas2.L). Synteny analyses of per1(E), per2(F), and npas2(G). Synteny analysis of X. laevis and X. tropicalis indicated that per1.S, per2.S, and npas2.S were lost from XLA3S, XLA5S, and XLA2S, respectively.

Image published in: Watanabe M et al. (2017)

Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V.

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