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Fig. 6. Identification, transcriptomic analysis, and sequence diversification of Pax family genes. (A) Phylogenetic tree analysis of X. tropicalis and X. laevis Pax family proteins. (B) RNA-seq analysis of differential expression of pax8 homeologs during development and in adult tissues. Transcriptomic data are shown in graphs similar to those in Fig. 1. (C) Comparison of amino acid sequences of mammalian and Xenopus Pax5 proteins. Magenta shading indicates substitution of a basic amino acid (R) with a non-polar amino acid (G) in the paired-box domain of Pax5.S. GenBank accession numbers of human and mouse Pax5 proteins used for this alignment are NP057953 and NP032808, respectively.

Image published in: Watanabe M et al. (2017)

Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V.

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