Xenbase Image ID: 154026

Fig. 4. Double mutant of nop and mip. (A) Phenotypically nop. (B) Phenotypically wildtype. (C) Phenotypically nop;mip double mutant. (D) Phenotypically mip. White arrows indicate normal gut-coiling pattern, which is clearly seen in nop background (A) but invisible in wildtype background (B). Red arrows indicate mirror-image gut-coiling pattern due to mip mutation, which is clearly seen in nop background (C) but not in wildtype background (D). The drawings in (A) and (C) indicate respectively wildtype gut coiling (right coil origin, counter-clockwise coil) pattern and mip gut coiling (left coil origin, clockwise coil) pattern. Image published in: Nakayama T et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Experiment + Assay Source Phenotypes and Disease Xtr.nop x Xtr.mip + NF46-47 (whole-mount microscopy) Fig. 4 C Anatomical Phenotype abnormal intestine morphology abnormally decreased number of iridophore absent iridophore decreased pigmentation in the epidermis decreased pigmentation in the eye Disease visceral heterotaxy Hermansky-Pudlak syndrome Larger Image Printer Friendly View

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