Xenbase Image ID: 154179

Fig. 4. Identification of cis-regulatory sequences, which contribute to the cdkn2c.S unique expression. (a) A comparison of non-coding sequences in cdkn2c genes among X. laevis chromosomes L and S and X. tropicalis. Upper panel: a genomic locus surrounded by dotted line indicates the conserved non-coding sequences (CNSs), which are retained in cdkn2c.S of X. laevis and cdkn2c of X. tropicalis, but are different from cdkn2c.L of X. laevis. Lower panel: sequences conserved between cdkn2c.S in X. laevis and cdkn2c in X. tropicalis are surrounded by black squares, and predicted binding motifs for transcription factors are indicated. (b) The CNSs in (a) were used for transgenic reporter analysis with X. laevis. Image published in: Tanaka T et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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