Xenbase Image ID: 154605

Figure 1. A: Schematic showing treatment paradigm. B: Frontal view of a representative Control treated with 1% DMSO. C: Frontal view of a representative embryo treated with JNK inhibitor. D: Frontal view of a representative embryo injected with control morpholino at the 1 cell stage. E: Frontal view of a representative embryo injected with JNK1 morpholino at the 1 cell stage. F: Schematic showing face transplant paradigm. G: Frontal view of a representative control transplant. H: Frontal view of a representative embryo with JNK1 morphant tissue transplanted to its orofacial region. I: Frontal view of a representative embryo with control morpholino injected into D12 blastomere at the 16 cell stage. J: Frontal view of a representative embryo with JNK1 morpholino injected into D12 blastomere at the 16 cell stage. K: A schematic of the JNK inhibitor treatment paradigm and stages examined by histology. L,M: Shows sagittal sections through the buccopharyngeal membrane just before JNK inhibitor treatment at stage 37/38 (two representative images). N,O: Shows sagittal sections through the buccopharyngeal membrane at stage 39 in controls (N) and JNK inhibitor treated (O). P,Q: Shows sagittal sections through the buccopharyngeal membrane at stage 40 in controls (N) and JNK inhibitor treated. perf, perforated; cg, cement gland; inj, injected; MO, morpholino; st, stage. Red dots outline the embryonic mouth. Image published in: Houssin NS et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

Return to previous page