Xenbase Image ID: 154715

Fig. 2. Syntenic analyses of Wnt signaling-related singletons inX. laevisandX. tropicalis. (A) Schematic view of the Wnt signaling pathway. Categories based on subcellular localization are indicated at the right. (B) Synteny around wnt2b. XLA2L retains conserved synteny around wnt2b with X. tropicalis chromosome 2 (XTR2), but several rearrangements may have occurred in XLA2S. (C) Synteny around rspo3. Complicated rearrangements were observed on both L and S chromosomes. (D) Comparison of sfrp4 loci. sfrp4.S was lost in a large deletion (~23 Mb) between velo1 and sept7 on XLA6S. (E) Comparison of genomic loci surrounding ppp2ca and tcf7. XLA3S retains conserved synteny with XTR3, even though LOC100489679 was deleted. On the other hand, XLA3L lost tcf7 and there was a large inversion close to vdac1.L. In addition, a pseudogene of ppp2ca.L, shown with a dashed box, was found between vdac1.L and LOC100488619.L. Magenta boxes show singletons involved in Wnt signaling, except hey2 in (C), which is related to Notch signaling. Double diagonal lines indicate a large gap between genes. Diagonal lines on the genome signify deletion of genes. Dashed lines represent putative inversion events. In each panel, only representative gene models are shown for comparison. Image published in: Michiue T et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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