Xenbase Image ID: 154718

Fig. 5. Correlations of epigenetic states and variable expression profiles. (A-C) Genome browser representations of ChIP-seq and DNA methylation data using X. laevis gastrula embryos (st10.5) demonstrated biased enrichment of H3K4me3 and p300 between homeologous genomic regions near axin2, cer1, and sfrp1. ChIP-seq results from biological replicates are shown separately. Green, H3K4me3; yellow, p300; gray, DNA methylation; bracket, strong enrichment of H3K4me3 on the promoter of the more strongly expressed homeolog; arrowhead, strong enrichment of p300 on enhancers of the more strongly expressed homeolog. (D) A vista plot represents sequence conservation in the genomic region around sfrp1 in X. laevis and X. tropicalis. The sequence of sfrp1.L was used as a reference. Light blue, UTR; dark blue, coding sequences; orange, conserved non-coding sequences. Dashed lines and magenta boxes in (C) and (D) correspond to each other. Image published in: Michiue T et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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