Xenbase Image ID: 154722

Fig. 9. Genes involved in heparan sulfate proteoglycans also showed variable expression profiles. (A) Schematic diagram of Glypican (Gpc) and Syndecan (Sdc). Solid lines and branches show core protein and glycosaminoglycan chains, respectively. N-deacetylase/N-sulfotransferase (NDST) removes N-acetyl groups from GlcNAc of nascent sugar chains (N-acetyl heparosan) and substitutes the free amino group with sulfate (N-sulfo HS). (B-D) Expression profiles of gpc1, gpc2, sdc4, and ndst1. Transcriptomic data are shown in graphs similar to those in Fig. 1. See text for detailed explanations of variable expression. Image published in: Michiue T et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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