Xenbase Image ID: 154777

Fig. 1. Neural and mesoderm induction by FGF. In situ hybridization analysis on early gastrula stage treated ectoderm cultured to the early tailbud stage. Untreated ectoderm (B,E,H), FGF-treated ectoderm (C,F,I), and the control whole embryos (A,D,G) were examined for expression of nrp-1 (purple) and muscle actin (M. actin, blue) (A-C); otx2 (purple) and En-2 (blue) (D-F); and Hox B9 (G-I). FGF induces both muscle actin and nrp-1, however, expression of the neural marker is not contingent upon muscle expression. The posterior marker, Hox B9, but not the anterior markers, otx2 or En-2, is induced by FGF. In A, the stong expression of muscle actin obscures the nrp-1 expression in the spinal cord. Image published in: Lamb TM and Harland RM (1995) Copyright © 1995. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue actc1.L actc, actna1, cardiac actin, cardiac alpha actin, muscle actin X. laevis Throughout NF stage 20 somite nrp1.L A5 antigen, LOC108718763, neuropilin, neuropilin-1, np-1, npn-1, nrp, nrp-1, pNPG152 X. laevis Throughout NF stage 20 neural tube otx2.L otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Throughout NF stage 20 anterior en2.L En-2, en2-a, en2-b, eng2, engrailed 2, engrailed homolog 2, engrailed-2, maben, xen2 X. laevis Throughout NF stage 20 presumptive midbrain-hindbrain boundary hoxb9.L hox 2.5, xhoxb9, XlHbox-6, XlHbox6 X. laevis Throughout NF stage 20 posterior Image source: Published Larger Image Printer Friendly View

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