Xenbase Image ID: 154812

FIG. 5. Effect of inhibition of BMP signaling pathway on expression of early mesodermal markers. AmTFR11 mRNA was injected into the marginal region of ventral blastomeres at the four-cell stage. Uninjected control embryo (A, C, and E), and AmTFR11-injected embryos (B, D, and F) were developed until early gastrula stage and subjected to whole-mount in situ analysis. The probe for goosecoid was used in A and B; the probe for Xpo was used in C and D; the probe for Xenopus brachyury was used in E and F. Views of the vegetal pole are shown and dorsal is up. Note that the expression of Xpo gene disappeared in the ventral part of embryo that received truncated BMP receptor mRNA (arrowheads) but that of brachyury gene, normally expressed through mesoderm, was not affected. Image published in: Suzuki A et al. (1994) Copyright © 1994. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tbxt.L bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury X. laevis Throughout NF stage 11 mesoderm post.L LOC108704914, Xpo X. laevis Throughout NF stage 11 marginal zone ventral marginal zone ventro-lateral marginal zone gsc.L goosecoid, gsc-a, gsc-b, Xgsc X. laevis Throughout NF stage 11 upper blastopore lip Image source: Published Larger Image Printer Friendly View

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