XB-IMG-154982
Xenbase Image ID: 154982
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Figure 5. Microtubule Perturbation Defocuses
the Actin Assembly Zone.
(A) Images from movies of oocytes injected
with OG-actin and wounded after no treatment
(control), nocodazole treatment (Nocodazole;
5 m; 1 hr), or taxol treatment (Taxol;
20 m; 1 hr). In controls, the zone of F-actin
polymerization remains tightly focused around
wounds; in nocodazole-treated oocytes it becomes
uneven and broadens; in taxol-treated
samples it spreads and then splits into two
rings (arrows). See Movies 13, 14, and 15.
(B) Confocal fluorescence images showing
distribution of F-actin (red) and microtubules
(green) in a taxol-treated oocyte subjected to
wounding. The microtubule and actin arrays
have split into concentric rings. Image published in: Mandato CA and Bement WM (2003) Copyright © 2003. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |