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Figure 2. Inhibition of L-leucine transporters in tested uptake buffers.L-leucine (Leu) uptake was tested in buffers containing 10 mM added competitors (BCH or amino acids). The Leu transporters (AATs) with affinity (Km (mM) values shown in Table 1) for the added competitors are indicated in the filled cells of the same color as the text for the named competitors. For Na+free uptake buffers, the Na+-dependent Leu AATs (i.e. require Na+ for Leu uptake) are indicated by ND. Additionally, responses of the Leu transporters for the competitor listed first for each uptake buffer are shown in the upper row and for the competitor listed second are shown in the lower row of filled cell(s). Clear boxes indicate AAT Leu uptake is unchanged due to addition of the indicated competitor and are used for AATs that transport Leu with affinities listed in Table 1 but do not transport the added competitor. aKm (mM) value is for low affinity kinetic component.

Image published in: Taslimifar M et al. (2017)

Copyright © 2017, The Author(s). This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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