Xenbase Image ID: 155738

Figure 7. Model of the evolution of the glucosinolate NPF transporter specificity.We propose that diversification of an ancestral high-affinity cyanogenic glucoside transporter (exemplified by MeCGTR1) lead to a dual-specificity transporter capable of transporting both cyanogenic glucosides and glucosinolates (exemplified by Me14G074000). With the emergence of glucosinolate biosynthesis, high-affinity, broad-specific glucosinolate transporters evolved (exemplified by CpGTRL1/2 and At/BrGTR1), which then further specialized to preferentially transport indole glucosinolates when indole biosynthesis emerged. Bidirectional arrow indicates an alternative model where high-affinity cyanogenic glucoside transporters emerged from the dual-specificity transporter (exemplified by Me14g074000). A. thaliana and C. papaya or M. esculenta diversified 108 MYA (median, 26 studies) or 72.1 MYA (median, 8 studies), respectively (Hedges et al., 2006). Branch points represent likely duplication events that led to new transporter substrate specificities. Striped pattern indicates a transporter that is unable to over-accumulate substrate compared to external media.DOI: http://dx.doi.org/10.7554/eLife.19466.025 Image published in: Jørgensen ME et al. (2017) © 2017, Jørgensen et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

Return to previous page