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FIGURE 4. BAF53a and Akirin2 involve in Xenopus neural development. (A-D) Co-injection with BAF53a mRNA (1.0 ng) rescues the expansion of Sox2 and Nkx6.2 in the Akirin2 morphants. LacZ mRNA was co-injected to trace the injected sides (stained red on the left sides). (E) Quantification of the effects of the injection of Akirin2 MO or co-injection of Akirin2 MO and BAF53a mRNA on the expression of Sox2, Nkx6.2, as shown in (A-D). (F-K) Co-injection with BAF53a mRNA (1.0 ng) or Akirin2 mRNA (1.0 ng) rescues the expansion of Sox2 and Nkx6.2 in the BAF53a morphants. LacZ mRNA was co-injected to trace the injected sides (stained red on the left sides). (L) Quantification of the effects of the injection of BAF53a MO or co-injection of BAF53a MO and BAF53a mRNA or Akirin2 mRNA on the expression of Sox2, Nkx6.2 as shown in (F-K).

Image published in: Liu X et al. (2017)

Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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