Xenbase Image ID: 155828

FIGURE 7. Proposed model for the coordination and temporal control of Xenopus neural development by Akirin2. In neural progenitor cells, Akirin2 acts antagonistically to Geminin in regulating Sox2 expression, and it maintain the neural precursor state after being recruited into BAF by BAF53a. Akirin2 also modulates N-tubulin expression by acting upstream of NeuroD, functioning in parallel with Ngnr1 during terminal neuronal differentiation when BAF53a and Geminin disappear. Image published in: Liu X et al. (2017) Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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