XB-IMG-156030
Xenbase Image ID: 156030
FIGURE 4 Hypothesis driven drug testing in genetically engineered Xenopus tropicalis tumor models. Straightforward delivery of targeted
nucleases (CRISPR/Cas9, TALEN) within the extrauterine developing Xenopus tropicalis embryo allows for generation of large cohorts (1100
animals) of tumor-bearing GEXM. Tumor-bearing GEXM can be directly subjected to drug treatment, by being reared in water with added
compound. Subsequently, the tumor responses can be analyzed in large cohorts adding power to statistical analyses Image published in: Naert T et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View |