Xenbase Image ID: 156917

Fig. S2. Lens cells are not affected upon loss of Fzd3, Alcam or Pax2. Transmission electron microscopy was used to examine lens and inner retina layers upon Fzd3 (A), Alcam (B) and Pax2 (C) depletion at embryonic stage 42, respectively. Specific cells are highlighted by dotted circles. Overview: A. Overview of the eyes including the location of close-ups in the anterior lens (a), posterior lens (b) and the ganglion cell layer (c). Scale bar: 100 µm. Specific cells are highlighted by dotted circles. Anterior und posterior lens (a, b): Neither the anterior, nor the posterior parts of the lens show a phenotype upon Fzd3, Alcam or Pax2 depletion. Scale bar: 5000 nm. Abbreviations: LE, lens epithelium; LFC, lens fiber cell. Number of embryos analyzed by TEM: Control MO, 9; Fzd3 MO, 4; Alcam MO, 4; Pax2 MO, 4. Image published in: Seigfried FA et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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