XB-IMG-156919
Xenbase Image ID: 156919
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Fig. S4.
Sequence of the alcam regulatory region and deletion constructs. A. −2.7kb regulatory promoter region (red) and 5′UTR region (blue) of alcam. AP1/ATF2 binding sites are indicated by blue boxes, Pax2 binding sites by yellow boxes. B.-E. Different deletion constructs are shown as insets of the alcam regulatory region. AP1/ATF2 binding sites are indicated by blue boxes, Pax2 binding sites by yellow boxes, deletion sites by black strokes. B. −2.7kb-∆ATF2/Pax2-luc promoter construct lacking a 265 bp long region containing seven AP1/ATF2 binding sites and two Pax2 sites. C. −2.7kb-∆Pax2-luc promoter construct lacking 55 bp that contains both Pax2 binding sites and ATF2 binding sites 3 and 4. D. −2.7kb-∆Pax2BS1-luc promoter construct lacking 6 bp, covering the Pax2 binding site 1. E. −2.7kb-∆Pax2BS2-luc promoter construct lacking a 20 bp long region, containing the Pax2 binding site 2 as well as the ATF2 binding site 4. Image published in: Seigfried FA et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |