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Fig. 3. The role of aPKC in organogenesis. has and nok mutants lack polarity and are defective in lateral plate mesoderm migration. (A and B) 30 hpf wild type embryo has correctly polarized LPM with asymmetric migration. (C and D) 30 hpf has and nok mutants show loss of epithelial polarity and defective migration. (E) Schematic of (A) showing correctly polarized LPM and asymmetric migration. (F) has and nok mutant have identical morphogenetic phenotypes. Used with permission. Image published in: Karner C et al. (2006) Copyright © 2006. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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