XB-IMG-157347
Xenbase Image ID: 157347
Figure 5. Two beta-parvalbumin genes are differentially expressed in ampullary organs versus neuromasts.(A) Phylogenetic analysis of selected vertebrate parvalbumin proteins shows three clades: the alpha-parvalbumins, plus two clades containing beta-parvalbumins: the first includes the mammalian beta-parvalbumins, i.e., oncomodulins, and chicken Pvalb3/thymic CPV3. One of the paddlefish lateral line-enriched parvalbumin genes encodes a protein that groups within the beta-parvalbumin clade containing the oncomodulins, so we have named it Pvalbβ1/Ocm. The other falls within the second beta-parvalbumin clade, so we have named it Pvalbβ2. (B) In situ hybridization shows that Pvalbβ1/Ocm is expressed in both ampullary organs and neuromasts, while (C) Pvalbβ2 is restricted to ampullary organs. Scale bars: 100 µm and 20 µm.DOI:
http://dx.doi.org/10.7554/eLife.24197.006 Image published in: Modrell MS et al. (2017) © 2017, Modrell et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |