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S3 Fig. Dynamic expression of different Hox genes in HoxB-4GR injected embryos.
(A) WISH for the expression of HoxD-1 (a-d and a’-d’), HoxB-4 (e-h and e’-h’), HoxC-6 (i-l and i’-l’) and HoxB-9 (m-p and m’-p’) in WT and HoxB4GR (activated at st.8) injected embryos. In both WT (a-d) and HoxB-4GR injected embryos (a’-d’), the expression of HoxD-1 was detected from st.10.5 to st.12. However, the expression of HoxB-4, HoxC-6 and HoxB-9 were detectable from st.10.5 (e’, n = 5/9), st.11 (j’, n = 7/11) and st.11.5 (o’, n = 5/8) respectively, whereas their endogenous expression started from st.11 (f), st.11.5 (k) and st.12 (p), respectively. (B) WISH for HoxD-1 expression at st.15 in WT (q) and HoxB-4GR injected (q’, n = 4/7) embryos. (C) Schematic showing dynamic expression of HoxD-1, HoxB-4, HoxC-6 and HoxB-9 in WT and HoxB-4GR injected embryos.
https://doi.org/10.1371/journal.pone.0175287.s004 Image published in: Zhu K et al. (2017) © 2017 Zhu et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license
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