XB-IMG-157689
Xenbase Image ID: 157689
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Figure 4 Effects of 1, 10-PNTL on the RPE cell-cell adhesion and Pax6 expression. Cell adhesion
profiles were examined using anti-connexin-43 and N-cadherin antibodies. (A, B and E, F) In the control
cultures, connexin-43 immunoreaction was detected in the epithelial zone, while N-cadherin was
found both in the epithelial and transitional zones. (C, D and G, H) In the presence of the inhibitor, no
positive staining for both antibodies was detected. (I–K) In the control culture, intense Pax6 immunoreactivity
was detected in the transitional zone, while no positive cells were detected in the presence of
the inhibitor (L–N). Asterisks indicate tissue explants and the dotted lines indicate the boundaries
between the explant and the epithelial zone. Four separate experiments were performed and the representative
data are shown in the figures. [Color figure can be viewed at wileyonlinelibrary.com] Image published in: Naitoh H et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View |