XB-IMG-157845
Xenbase Image ID: 157845
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Fig. 1. FoxD1 protein is a more potent neural anteriorizer when canonical Wnt activity is inhibited. (A) Morphology of tail-bud stage 33-34 (n=27) embryos injected at the one-cell stage with foxd1 (10 pg) or dkk1 (30 pg) mRNAs. (B) Ectopic FoxD1 protein caused a bent-neuralized phenotype in some of the embryos (n=35, 17% bent). (C) Ectopic Dkk1 protein reduced posterior neural regions and enlarged anterior structures in 94% of the embryos (n=33). (D) Co-expression of Foxd1/Dkk1 proteins strongly eliminated posterior neural structures, inducing a highly anteriorized embryo body, forming radial heads/cement glands in 79% of the embryos (n=28). Image published in: Polevoy H et al. (2017) Copyright © 2017. Reproduced with permission of the Publisher, University of the Basque Country Press. Larger Image Printer Friendly View |