Xenbase Image ID: 157983

Fig. 6. The RGD motif is not required for the dorsalizing activity of xDel1. (A) Schematic of mutant xDel1 constructs (xDel1-E2 type; see Materials and methods). EGF, EGF repeat; RGD, RGD motif; Discoidin, Discoidin domain. (B) RT–PCR analysis of RNA-injected VMZ explants for dorsalizaton assay (late neurula stage-equivalent): lane 1, whole embryo; lane 2, control DMZ; lane 3, control VMZ; lane 4, wild-type xDel1-injected VMZ; lane 5, xDel1-RGE mutant-injected VMZ; lane 6, xDel1-delN mutant-injected VMZ; lane 7, xDel1-delC mutant-injected VMZ. Image published in: Arakawa A et al. (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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