Xenbase Image ID: 158018

Trunk-skin regeneration and wound healing after excision. A: Illustration of a metamorphosed froglet; the red rectangle shows the location for skin excision. B: The skin wound immediately after excision. C: A section of intact trunk skin stained with Elastica van Gieson and Alcian blue. Epi, epidermis; der, dermis; mg, mucous gland; sg, serous gland; mus, muscle (n = 4). D'–G': Magnified views of the rectangles in D–G. Time after incision: D,D', 0 hr (immediately after skin excision) (n = 4); E,E', 24 hr (n = 4); F, F', 4 days (n = 4); G,G' 10 days (n = 4); H,H', 1 month after excision (n = 3). Black arrowheads (B) indicate the wound site. Open arrowheads (D–H) indicate the right-hand border of the wound. Black arrows (E'–G') indicate the basement membrane of the epidermis. Asterisk (H') indicates an exocrine gland duct. B: Bar = 1 mm. C–H,D'–H': Bar = 50 µm. Image published in: Otsuka-Yamaguchi R et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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