Xenbase Image ID: 158021

Head-skin regeneration and wound healing after excision. A: Illustration of a metamorphosed froglet; the red rectangle shows the excision location. B: The skin wound immediately after excision. C: A section of intact head skin, stained with Elastica van Gieson and Alcian blue. Epi, epidermis; der, dermis; mg, mucous gland; sg, serous gland; sku, skull (n = 4). D'–H': Magnified views of the rectangles in D–H. Time after excision: D, D', 0 hr (immediately after excision) (n = 3); E,E', 24 hr (n = 5); F,F', 4 days (n = 5); G,G', 10 days (n = 5); H,H', 1 month after excision (n = 4). Black arrowheads (B) indicate the wound site. Open arrowheads (D–H) indicate the right-hand border of the wound. Black arrow (G') indicates maturing secretion gland. B: Bar = 1 mm. C–H, D'–H': Bar = 50 µm. Image published in: Otsuka-Yamaguchi R et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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