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FIGURE 5. Pitx3 represses the Th (tyrosine hydroxylase) promoter. The Th reporter (plasmid CMV-HcRed/Th-DsRed) was tested, under conditions of presence or absence of forskolin, to see how it responded to vectors for pitx3 absent (IRES-GFP), pitx3 protein (pitx3-IRES-GFP), or pitx3mutHD expressing a homeodomain mutant (pitx3mutHD-IRES-GFP). ANOVA demonstrated that statistically significant differences existed. A post hoc Tukey test determined specifically which comparisons were significant and P values are reported above. ns, no significant difference

Image published in: Hooker LN et al. (2017)

Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons.

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