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Figure 6. The Th (Tyrosine hydroxylase) promoter binding motif for pitx3 is important for repression. Wild-type and mutant Th reporters (wt: CMV-HcRed/Th-DsRed; mutant: CMV-HcRed/Thmut-350-DsRed) were tested under conditions of the presence or absence of pitx3 (absent: plasmid IRES-GFP; present: plasmid pitx3-IRES-GFP). ANOVA demonstrated that statistically significant differences existed. A post hoc Tukey test determined specifically which comparisons were significant and P values are reported above. ns, no significant difference. Image published in: Hooker LN et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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