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 Figure 8. lhx1 promoter activation by pitx3. Vectors for pitx3 absent (IRES-GFP), pitx3 protein (pitx3-IRES-GFP), or pitx3mutHD expressing a homeodomain mutant (pitx3mutHD-IRES-GFP) were tested for their ability to activate a wild-type lhx1wt promoter-driven DsRed reporter (CMV-HcRed/lhx1-DsRed) and a pitx3 binding motif mutant lhx11mut-709 promoter-driven DsRed reporter (CMV-HcRed/lhx1mut-709-DsRed). ANOVA demonstrated that statistically significant differences existed. A post hoc Tukey test determined specifically which comparisons were significant and P values are reported above. ns, no significant difference.

Image published in: Hooker LN et al. (2017)

Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons.

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