Xenbase Image ID: 158179

FIGUTRE 8. Genes repressing or being downregulated during cancer development/progression show varied expression patterns in Xenopus embryos. A, spatial expression patterns were examined with WMISH. Embryos at the same stages as shown in Fig. 6 were used and presented in the same way as in Fig. 6. A, anterior; ad, adenohypophysial placode; ba, branchial arch; cg, cement gland; cgp, cement gland primordium; ep, epidermis; ev, ear vesicle; ey, eye; fb, forebrain; hb, hindbrain; le, lens; mb, midbrain; mhb, midbrain-hindbrain boundary; nc, notochord; nu, neuron; np, neural plate; nt, neural tube; P, posterior; pn, pronephros; pm, paraxial mesoderm; ps, posterior somite; sm, somite; tg, trigeminal nerve. B, summary of the relatedness of gene expression/function in cancer and their expression. Image published in: Zhang Z et al. (2017) Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue apc.S xapc X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate apc.S xapc X. laevis Sometime during NF stage 26 to NF stage 32 brain forebrain midbrain hindbrain central nervous system eye branchial arch trigeminal ganglion head pharyngeal region neurogenic placode arid1a.S LOC108707477, LOC108708921 X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate neural tube arid1a.S LOC108707477, LOC108708921 X. laevis Sometime during NF stage 26 to NF stage 32 brain forebrain midbrain hindbrain central nervous system eye branchial arch head pharyngeal region intermediate mesoderm axin1.S axin, fused, xAxin X. laevis Sometime during NF stage 15 to NF stage 20   axin1.S axin, fused, xAxin X. laevis Sometime during NF stage 26 to NF stage 32   brms1.L X. laevis Sometime during NF stage 15 to NF stage 20   brms1.L X. laevis Sometime during NF stage 26 to NF stage 32   casp9.S caspase 9, caspase-9, caspase9, iCasp9, xCaspase-9 X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate casp9.S caspase 9, caspase-9, caspase9, iCasp9, xCaspase-9 X. laevis Sometime during NF stage 26 to NF stage 32 brain forebrain midbrain hindbrain head eye pharyngeal region somite central nervous system cdkn1a.L cip1, p16Xic2, p21 X. laevis Sometime during NF stage 15 to NF stage 20 cement gland primordium ectoderm cdkn1a.L cip1, p16Xic2, p21 X. laevis Sometime during NF stage 26 to NF stage 32 cement gland somite eye otic vesicle lens placode cdkn1b.S cdkn4, kip1, LOC108710741, men1b, men4, p16Xic3, p17Xic3, p27kip1 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate cdkn1b.S cdkn4, kip1, LOC108710741, men1b, men4, p16Xic3, p17Xic3, p27kip1 X. laevis Sometime during NF stage 26 to NF stage 32   cdkn2b.L cdk4l, ink4b, mts2, p15, p15ink4b, tp15 X. laevis Sometime during NF stage 15 to NF stage 20 neural plate cdkn2b.L cdk4l, ink4b, mts2, p15, p15ink4b, tp15 X. laevis Sometime during NF stage 26 to NF stage 32 head pharyngeal region chfr.L X. laevis Sometime during NF stage 15 to NF stage 20 neural plate neuroectoderm chfr.L X. laevis Sometime during NF stage 26 to NF stage 32 brain forebrain midbrain hindbrain central nervous system head pharyngeal region otic vesicle eye paraxial mesoderm dlc1.S LOC108698560, LOC108706599, rhogap7 X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate dlc1.S LOC108698560, LOC108706599, rhogap7 X. laevis Sometime during NF stage 26 to NF stage 32   dmbt1.S glycoprotein 340, gp-340, gp340, hensin, muclin, salivary agglutinin X. laevis Sometime during NF stage 15 to NF stage 20 ectoderm dmbt1.S glycoprotein 340, gp-340, gp340, hensin, muclin, salivary agglutinin X. laevis Sometime during NF stage 26 to NF stage 32   gas1.L X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate paraxial mesoderm epidermis gas1.L X. laevis Sometime during NF stage 26 to NF stage 32 brain midbrain hindbrain central nervous system somite otic vesicle head hexim1.L X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate hexim1.L X. laevis Sometime during NF stage 26 to NF stage 32 pronephric nephrostome head eye pharyngeal region tail bud otic vesicle brain hic1.L X. laevis Sometime during NF stage 15 to NF stage 20 neuron neuroectoderm hic1.L X. laevis Sometime during NF stage 26 to NF stage 32 trigeminal ganglion notochord mgmt.L LOC108697181 X. laevis Sometime during NF stage 15 to NF stage 20   mgmt.L LOC108697181 X. laevis Sometime during NF stage 26 to NF stage 32   pbrm1.L LOC108705353, pb1 X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate pbrm1.L LOC108705353, pb1 X. laevis Sometime during NF stage 26 to NF stage 32 central nervous system brain eye forebrain midbrain hindbrain pharyngeal region otic vesicle pdcd4.L h731 X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate ectoderm pdcd4.L h731 X. laevis Sometime during NF stage 26 to NF stage 32 eye lens placode midbrain-hindbrain boundary perp.S kcp1, krtcap1, pigpc1, thw X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm perp.S kcp1, krtcap1, pigpc1, thw X. laevis Sometime during NF stage 26 to NF stage 32   phlpp1.S phlpp, plekhe1, scop X. laevis Sometime during NF stage 15 to NF stage 20   phlpp1.S phlpp, plekhe1, scop X. laevis Sometime during NF stage 26 to NF stage 32   pten.L X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate ectoderm pten.L X. laevis Sometime during NF stage 26 to NF stage 32 head brain eye pharyngeal region central nervous system otic vesicle branchial arch forebrain midbrain hindbrain st13.S X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate st13.S X. laevis Sometime during NF stage 26 to NF stage 32 brain hindbrain central nervous system eye head pharyngeal region otic vesicle midbrain intermediate mesoderm tet2.L X. laevis Sometime during NF stage 15 to NF stage 20   tet2.L X. laevis Sometime during NF stage 26 to NF stage 32 brain forebrain midbrain midbrain-hindbrain boundary central nervous system head eye pharyngeal region tgfbr1.S aat5, acvrlk4, alk-5, alk5, lds1a, lds2a, LOC108719029, skr4, tgfr-1, TrR-1, xTrR-1 X. laevis Sometime during NF stage 15 to NF stage 20   tgfbr1.S aat5, acvrlk4, alk-5, alk5, lds1a, lds2a, LOC108719029, skr4, tgfr-1, TrR-1, xTrR-1 X. laevis Sometime during NF stage 26 to NF stage 32   tp53.L p53, Trp248, tumor suppressor p53, Xp53, Xrel3 X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate tp53.L p53, Trp248, tumor suppressor p53, Xp53, Xrel3 X. laevis Sometime during NF stage 26 to NF stage 32 brain midbrain hindbrain midbrain-hindbrain boundary head eye pharyngeal region central nervous system otic vesicle branchial arch presomitic mesoderm tp73.L LOC108696624, LOC108697705, xP73 X. laevis Sometime during NF stage 15 to NF stage 20   tp73.L LOC108696624, LOC108697705, xP73 X. laevis Sometime during NF stage 26 to NF stage 32   tp53bp2.L X. laevis Sometime during NF stage 15 to NF stage 20 neuroectoderm neural plate cement gland primordium tp53bp2.L X. laevis Sometime during NF stage 26 to NF stage 32 brain forebrain midbrain midbrain-hindbrain boundary head eye pharyngeal region pronephric mesenchyme otic vesicle central nervous system txnip.L X. laevis Sometime during NF stage 15 to NF stage 20   txnip.L X. laevis Sometime during NF stage 26 to NF stage 32 somite ventral mesoderm Image source: Published Larger Image Printer Friendly View

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