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Supplementary Figure 9 | Combined effects of cadherin expression and ephrin signaling.
(a) Dissociation assay showing decreased cell-cell adhesion for mesoderm explants upon ephrin ectopic expression and rescue by C-cadherin coexpression. Results are average from eight independent experiments. (b) Separation of mesoderm tissues induced by treatment of the explants with soluble ephrin-Fc is not sensitive to C-cadherin overexpression. Numbers on top correspond to separated/total number of explants, from three experiments. Student’s t-test, color code as above. Image published in: Canty L et al. (2017) © The Author(s) 2017. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |