Xenbase Image ID: 158637

Fig. 4. Temporal expression of hox genes during developmental stages 8 to 40. (A) Expression levels of 50 genes that had TPM morethan 5.0 at some point was normalized so that the peak TPM is 1. By clustering analysis, genes were grouped into eight “expressiongroups” (ExpG). hoxb4.L was exceptional, since the egg showed the highest value, but to observe zygotic expression, it was normalizedto the value at stage 40. Nevertheless, because of its unique pattern, this was not included in any ExpG. (B) Expression profiles of eachExpG. The patterns are mostly overlapping. (C) Summary of expression profiles. Four of the six PG1 (labial) genes are categorized inExpG1 (the other two are ExpG4), and expressed early, and PG11 to 13 genes in the posterior group are expressed late (ExpG8) or notuntil after stage 40, whereas the pb, central, and posterior PGs 9 and 10 showed no temporal collinearity. Asterisks indicate homeologsthat belong to the same ExpG. Image published in: Kondo M et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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