Xenbase Image ID: 158751

Figure 1. Four Novel Tcf/Lef-like Genes Expressed in Xenopus Embryos (A) Four highly homologous gene products (XTcf-3, XTcf-3b, XTcf-3c, and XTcf-3d) were identified in a stage-17 embryonic cDNA library. These are compared with human Tcf-1 and Lef-1. The HMG domains are boxed, as is the conserved N-terminal region. The sequences diverge in the region C-terminal to the HMG box. A putative nuclear localization signal (NLS) overlaps with the C-terminus of the HMG box (asterisks; Prieve et al. 1996). (B) XTcf-3 and β-catenin constructs used in this study. Image published in: Molenaar M et al. (1996) Copyright © 1996. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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