Xenbase Image ID: 158857

Figure 1 Axis formation is affected by siamois fusions. (A) Schematic of the siamois fusion constructs. A C-terminal region of siamois (residues 122–246), containing the homeodomain (HD), was fused to the engrailed repressor (residues 1–298) (Eng-Sia) or the VP16 activator (residues 410–490) (VP16-Sia). At the four-cell stage, one ventral (B–E, J–M) or two dorsal (F–I, N–Q) blastomeres were injected with 30 pg of β-galactosidase (B, F, J, N), siamois (C, G, K, O), VP16-Sia (D, H, L, P), or Eng-Sia (E, I, M, Q) mRNA. (J–Q) Transverse sections. See Table 1 for quantitation. Image published in: Kessler DS (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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