XB-IMG-158933
Xenbase Image ID: 158933
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Figure 1. Xenopus Follistatin 319 Is a Secreted
Protein
(A) Nucleotide and deduced amino acid sequence
of XFS-319. The signal sequence is
underlined; the follistatin modules are boxed.
(B) Comparison of relative positions and numbers
of follistatin modules in testican, osteonectin,
SC1 , and agrin. The open reading frames
are presented as boxes and follistatin modules
as filled boxes. Each box is drawn to scale except
for the long carboxy-terminal box of agrin,
which is denoted by two diagonal lines.
(C) XFS-319 is a secreted protein. Capped synthetic
RNA encoding XFS-319 was used in a
reticulocyte lysate for in vitro translation or injected
in Xenopus oocytes. The conditioned
medium from control uninjected (lane 1) and
injected (lane 2) oocytes as well as the reticulocyte
lysate (lane 3) was fractionated by SDSPAGE.
In both cases, a protein of about 32 kd
was made from the follistatin mRNA. Image published in: Hemmati-Brivanlou A et al. (1994) Copyright © 1994. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |