XB-IMG-159024
Xenbase Image ID: 159024
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Fig. 9. Proposed model showing vgll3 functions in trigeminal placode/nerve
formation and CNC migration. Vgll3 acts via secreted molecules like WNT or FGF
on neural border expressed genes to control the formation of branchial arches and
trigeminal placode. Vgll3 can interact with ets1 and sustain pax3/zic1 expression and
their downstream target genes. Ant, anterior; Post, posterior; ba1, branchial arch1;
CNC, cranial neural crest; RA, retinoic acid. Image published in: Simon E et al. (2017) © 2017. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |