Xenbase Image ID: 159399

Figure 2 Expression of Pax-6 in the developing brain. In all panels except (E,F), anterior is to the right. In all panels except (A), (C), and (H), dorsal is up; in (A,C,H), dorsal is facing the viewer. (A) The earliest apparent staining pattern of Pax-6 at the neural plate stage (stage 14); arrow indicates the medial stripe. (B,C) A lateral (B) and dorsal (C) view of a stage 23 embryo. The arrowhead indicates the optic vesicle in (B), while the arrows indicate the two rhombomere-specific stripes in the hindbrain in (C). The midbrain staining is visible in (C) medial to the dotted white lines. (D) A lateral low-power view of a stage 28 embryo. The arrowhead indicates the gap in Pax-6 expression in the mesencephalon (optic tectum). The arrow points out the staining in the presumptive oculomotor nucleus. The dotted white line serves to distinguish the eye from the telencephalon/diencephalon. The developing eye also shows Pax-6 expression. (E) A transverse section of a stage 28 embryo at the level of the diencephalon: the arrow indicates staining in the dorsal diencephalon. (F) A transverse section of a stage 28 embryo through the spinal cord. The arrow indicates Pax-6 staining in the ventricular zone. N notochord. (G) A lateral view of a stage 42 embryo. The arrowhead shows a decrease of Pax-6 expression in the spinal cord, while the arrow shows a decrease of expression in the outermost layer of the retina. (H,I) A dorsal (H) and lateral (I) view of a stage 42 brain dissected free of surrounding tissue. The arrowhead in (H) points to staining in the olfactory bulb, while the arrows point to the rhombomere-specific staining. Abbreviations in (I): My meyelencephalon, Me mesencephalon, Di diencephalon, Te telencephalon. Scale bar is 200 mm in all except (E,F) (100 mm). Image published in: Hirsch N and Harris WA (1997) Copyright © 1997. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue pax6.L an2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6 X. laevis Throughout NF stage 14 neural plate anterior neural fold pax6.L an2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6 X. laevis Throughout NF stage 23 eye eye primordium pax6.L an2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6 X. laevis Throughout NF stage 28 forebrain central nervous system brain spinal cord eye diencephalon telencephalon pax6.L an2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6 X. laevis Throughout NF stage 42 forebrain eye diencephalon telencephalon Image source: Published Larger Image Printer Friendly View

Return to previous page