Xenbase Image ID: 159421

Figure 2. Two modes of convergent extension. (a) Driving force and cell movements in the crawling mode. The cells elongate along the mediolateral axis (short axis of the elongating tissue) and crawl and tug the neighboring cells by actin-rich protrusions located at both tips of the elongated cells (red parts) that lead to the intercalating movements. (b, b′) Driving force and cell movements in the contraction mode. Activation of actomyosin along the cell–cell junction constricts the junction (red line) and pulls the neighboring cells (dark and light gray colored cells) to the center in this scheme. The actomyosin is activated at the cell–cell junction aligning along the short axis of the elongating cell. After the neighboring cells meet together, these two cells construct a new cell–cell junction (junction remodeling, green short line), and actomyosin starts constricting the other cell–cell junction aligned to the short axis of the tissue. Repeating these events allows the cell to establish intercalating movements. (B′) is a scheme of rosette formation. Image published in: Shindo A (2018) © 2017 The Authors. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license Larger Image Printer Friendly View

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