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S11 Fig. Expression dynamics of homeologous gene copies during neurulation. Expression pattern comparison between selected homeologous transcription factor pairs. The spatial and temporal expression of both copies of pax3, sox10, and six3 highly correlate in all 79 tissue samples (R2 > 96, p-value = 0). Other genes exhibit expression level differences over different time points (id2, zic1, six4) or across space and time (snai2, id2). The lowest correlations observed between the displayed homeologous pairs are snai2.l and snai2.s (R2 = 0.60, p-value = 4e-09) and zic1.s and zic1.l (R2 = 0.65, p-value = 4e-11). The parentheses after the gene names correspond to the co-expression groups assigned by weighted gene correlation network analy- sis (WGCNA). See S11 Table for numerical data. Image published in: Plouhinec JL et al. (2017) © 2017 Plouhinec et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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