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XB-IMG-159665

Xenbase Image ID: 159665

Fig. 2. Fgf8, krt62.L and Krt12.6.S expression in the froglet blastema. The middle bud blastema was sectioned. In situ hybridization (for Fgf8 or krt62.L) and immunofluorescence (for Krt12.6.S) were performed on an identical section. (A) Histological observation. B–G are the higher magnification views of the arrowed region in A. (B–D) krt62.L and Krt12.6.S expression. D is the merged image with the high magnification of B and C. Krt12.6.S color was changed using Photoshop for easier recognition. (E–G) fgf8 and Krt12.6.S expression. G is the merged image with the high magnification of E and F. Krt12.6.S color was changed by Photoshop for easier recognition. The dotted lines in D and G indicate the border of the blastema epithelium. Scale bars in A, B and D are 500, 200 and 100 µm, respectively.

Image published in: Satoh A et al. (2017)

Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V.

GeneSynonymsSpeciesStage(s)Tissue
krt12.6.Ladult-specific keratin, xak-cX. laevisThroughout NF stage 66regenerating limb
blastema
apical epithelial cap
fgf8.LAIGF, FGF-8, fgf-8b, fgf8a, fgf8b, MGC79739, Xfgf-8, Xfgf8X. laevisThroughout NF stage 66regenerating limb
apical mesenchyme
blastema
krt62.Lkrt5.5, larval keratin, xlkX. laevisThroughout NF stage 66regenerating limb
apical mesenchyme
blastema

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