Xenbase Image ID: 159720

Fig. 5. Activation of the LEHD reporter in the VBI. (A,B) Comparison between the transgenic DEVD and LEHD reporter embryos (X. tropicalis) revealed overlapping GFP-positive regions, such as the brain and eye. However, only the LEHD embryos had GFP expression in the VBI, where the primitive blood is formed (arrowheads). (C–D) As development continued, the GFP signal in the VBI intensified and localized in the typical outline of the VBI (ventral view in D). (E) At stage 38–40, GFP-positive cells entered the blood circulation via the vitteline veins. Circulating GFP-expressing blood cells could be detected throughout the embryo (arrowhead). (F) Individual GFP-expressing erythrocytes collected and imaged at stage 42. Image published in: Tran HT et al. (2017) Copyright © 2017. Image reproduced with permission of the Publisher, The Company of Biologists Ltd. Larger Image Printer Friendly View

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