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Fig. 6. Schematic representation of the vertex model. (A) The mechanical potentials are shown with five cells. (B) Effect of the Ca2+ transient is described. The Ca2+ transients at the single-cell (i) and multicellular (ii) levels are shown. Cells marked by blue stars are activated. Activated cellular edges in an activated cell are marked by arrows (iii). (C,D) The constrictive nature of the apical cell surface with a ratchet-like stabilization is modeled by two differential equations. The regulation of the natural cell area and of the natural cell perimeter are described in C and D, respectively. The bright orange regions in C are the actual cell surface area, and the dark orange regions correspond to the natural cell surface area. The bright orange lines in D are the actual cell perimeter, and the dark orange broken lines correspond to the natural perimeter. See main text and Supplementary Materials and Methods for the detail.

Image published in: Suzuki M et al. (2017)

Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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