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Fig. 1. Chemical structures of chloride channel antagonists. The star indicates the chiral center for both isoxazoline molecules. The biologically active compound lotilaner is the S-enantiomer while the R-enantiomer (AHC-2229544) is inactive. Fluralaner is a racemic mixture containing both enantiomers Image published in: Rufener L et al. (2017) © The Author(s). This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |